The lights go up and the hair comes off starting at 2 p.m. Saturday in the annual St. Baldrick’s Foundation fund-raiser for childhood cancer treatment and research. Headquartered at McMullan’s Irish Pub at 4650 W. Tropicana Ave., this year’s event includes participation by Fado at 9470 S. Eastern Ave. and Nine Fine Irishman inside the New York New York.

Daughter Amelia is scheduled to shave my lopsided noggin at 4 p.m. The event lasts until early Sunday morning and will include appearances by members of Cirque du Soleil and a host of celebrity emcees.

St. Baldrick’s raises the most money of any private charity for childhood cancer research.